American Airlines, Alaska Airlines, and JetBlue Airways have all told their employees that they will need to get vaccinated against COVID-19 by December 8th. President Biden’s sweeping vaccine requirement for federal contractors will include major airlines as they transport government employees and provide their services for emergency flights. These companies do say that a vast majority of their employees are already vaccinated, and they are strongly urging their staff to get vaccinated before the busy holiday season begins.
See "Major airlines tell employees they must get vaccinated", Leslie Josephs, CNBC, October 4, 2021